NAD+ precursors boost cellular energy but consume methyl groups in the process. TMG donates methyl groups to replenish what NAD+ synthesis uses, preventing methylation depletion.
This pair requires two separate supplements. Both are needed for the synergy to work.
Nicotinamide mononucleotide (NMN) is a direct precursor to NAD+, the coenzyme critical for cellular energy production and DNA repair. Levels decline with age.
View on Amazon →Trimethylglycine donates methyl groups via the BHMT pathway, replenishing the methylation pool that NAD+ synthesis depletes. The essential companion to any NAD+ precursor.
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Coming soonHow to take this pair: Take 250-1,000 mg NMN in the morning on an empty stomach to align with circadian NAD+ rhythms. Take 500-1,000 mg TMG at the same time so methyl donors are available as NAD+ synthesis proceeds. Start TMG at 500 mg and increase gradually. People with MTHFR variants should monitor for overmethylation symptoms.
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